Clinical Trials

As a cancer researcher in Colorado, Rocky Mountain Cancer Centers has a research program which provides experimental therapeutics to patients with cancer. To learn more about RMCC's open clinical trials, please review the trials listed below.

If you have questions about clinical trials, please visit our Frequently Asked Questions page for more information.

Find a Trial by Cancer Type
Select Cancer Type:

Current Clinical Trials

014
Mesothelioma
A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Oral Suberoylanilide Hydroxamic Acid (Vorinostat, MK-0683) in Patients with Advanced Malignant Pleural Mesothelioma Previously Treated with Systemic Chemotherapy Click here to apply for this clinical trial.

09-214
Waldenstrom's Macroglobulinemia

Phase II Study of Everolimus (RAD001) in Primary Therapy of Waldenstrom's Macroglobulinemia

Click here to apply for this clinical trial.

16201
Chronic Lymphocytic Leukemia
A Phase 1b/2 Open Label Study to Evaluate the Safety and Efficacy of TRU-016 in Combination with Bendamustine vs. Bendamustine Alone in Patients with Relapsed Chronic Lymphocytic Leukemia Click here to apply for this clinical trial.

2009-APBI
Breast Cancer

A Phase III Randomized Study Comparing Intensity Modulated Planning versus 3-Dimensional Planning for Accelerated Partial Breast Radiotherapy

Click here to apply for this clinical trial.

C14004
Non-Hodgkin Lymphoma (NHL)
A Phase 2 Trial of MLN8237, an Oral Aurora A Kinase Inhibitor, in Adult Patients with Aggressive Non-Hodgkin's Lymphoma Click here to apply for this clinical trial.

C16002
Hodgkin Lymphoma, Lymphoma
An Open-Label, Dose-Escalation Phase 1 Study of MLN9708, A Second-Generation Proteasome Inhibitor, in Adult Patients with Lymphoma Click here to apply for this clinical trial.

CA184043
Prostate Cancer
A Randomized, Double-Blind, Phase III Trial Comparing Ipilimumab vs Placebo Following Radiotherapy in Subjects with Castration Resistant Prostate Cancer That Have Received Prior Treatment with Docetaxel Click here to apply for this clinical trial.

CA184045
Melanoma
A Multicenter Treatment Protocol for Compassionate Use of Ipilimumab (BMS-734016) Monotherapy in Subjects with Unresectable Stage III or Stage IV Melanoma Click here to apply for this clinical trial.

Carter 2005-01
Solid Metastatic Tumors; Prostate, Breast, Brain, Lung, Liver, Colorectal
A prospective investigation of definitive targeted therapy for solid malignancies with oligometastases Click here to apply for this clinical trial.

CLBH589CUS57T
Waldenstrom's Macroglobulinemia
Phase II trial of LBH589 (panobinostat) in relapsed or relapsed and refractory Waldenstrom's Macroglobulinemia Click here to apply for this clinical trial.

CRAD001N2301
Diffuse Large B-Cell Lymphoma
A randomized, double-blind, placebo-controlled, multi-center phase III study of RAD001 adjuvant therapy in poor risk patients with Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 versus matching placebo after patients have achieved complete response with first-line rituximab-chemotherapy [PILLAR-2]  Click here to apply for this clinical trial.

CRAD001NUS65
Hodgkin Lymphoma
An Open-Label, Single-Arm Phase II Study of Everolimus (RAD001) in Patients with Relapsed/]Refractory Classical Hodgkin Lymphoma Click here to apply for this clinical trial.

CSTI571BUS227 reGISTry
GIST

Gastrointestinal Stromal Tumor (GIST) Registry Protocol

Click here to apply for this clinical trial.

CTSU/CALGB 10603
Acute Myeloid Leukemia (AML)
A Phase III Randomized, Double-Blind Study of Induction (Danorubicin/Cytarabine) and Consolidation (High-Dose Cytarabine) Chemotherapy + Midostaurin (PKC412) (IND# 101261) or Placebo in Newly Diagnosed Patients < 60 Years of Age with FLT3 Mutated Acute Myeloid Leukemia (AML) Click here to apply for this clinical trial.

CTSU/CALGB 30610
Lung Cancer, Small Cell Lung Cancer
Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin and Etoposide Click here to apply for this clinical trial.

CTSU/CALGB 40502
Breast Cancer
A Randomized Phase III Trial of Weekly Paclitaxel Compared to Weekly Nanoparticle Albumin Bound Nab-Paclitaxel or Ixabepilone Combined with Bevacizumab as First -Line Therapy for Locally Recurrent or Metastatic Breast Cancer Click here to apply for this clinical trial.

CTSU/CALGB 40503
Breast Cancer

A Randomized Phase III Trial of Endocrine Therapy Alone or Endocrine Therapy Plus Bevacizumab (NSC 704865; IND 7921) For Women with Hormone Receptor-Positive Advanced Breast Cancer

Click here to apply for this clinical trial.

CTSU/CALGB 50303
Non-Hodgkin Lymphoma (NHL), Diffuse Large B-Cell Lymphoma
Phase III Randomized Study of R-CHOP versus Dose Adjusted EPOCH-R with Molecular Profiling in Untreated De Novo Diffuse Large B-cell Lymphomas Click here to apply for this clinical trial.

CTSU/CALGB 70604
Breast Cancer, Prostate, Multiple Myeloma
A Randomized, Phase III Study of Standard Dosing versus Longer Dosing Interval of Zoledronic Acid in Metastatic Cancer (Breast, Prostate, Multiple Myeloma) Click here to apply for this clinical trial.

CTSU/CALGB 90601
Transitional Cell Carcinoma
A Randomized, Double-blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma Click here to apply for this clinical trial.

CTSU/GOG-0212
Advanced Ovarian or Primary Peritoneal Cancer
A Randomized Phase III Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or Xyotax (CT-2103) Vs No Treatment Until Documented Relapse in Women With Advanced Ovarian or Primary Peritoneal Cancer Who Achieve A Complete Clinical Response To Primary Platinum/Taxane Chemotherapy. Click here to apply for this clinical trial.

CTSU/NCCTG N063D
Breast Cancer
Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation Study: A Randomised, Multi-centre, Open-label, Phase III Study of Adjuvant Lapatinib, Trastuzumab, Their Sequence and Their Combination in Patients with HER2/ErbB2 Positive Primary Breast Cancer (ALTTO) Click here to apply for this clinical trial.

CTSU/NCCTG N0733
Breast Cancer
Randomized Phase II Trial of Capecitabine and Lapatinib with or without IMC-A12 in Patients with HER2 Positive Breast Cancer Previously Treated with Trastuzumab and an Anthracycline and/or a Taxane Click here to apply for this clinical trial.

CTSU/SWOG S0600
Colorectal Cancer
Phase III Trial of Irinotecan-Based Chemotherapy Plus Cetuximab (NSC-714692) or Bevacizumab (NSC-704865) as Second-Line Therapy for Patients with Metastatic Colorectal Cancer who have Progressed on Bevacizumab with either FOLFOX, OPTIMOX, or XELOX Click here to apply for this clinical trial.

CTSU/SWOG S0702
Bone Metastases
A Prospective Observational Multicenter Cohort Study to Assess the Incidence of Osteonecrosis of the Jaw (ONJ) in Cancer Patients with Bone Metastases Starting Zoledronic Acid Treatment Click here to apply for this clinical trial.

CTSU/SWOG S0777
Multiple Myeloma
A Randomized Phase III Trial of CC-5-13 (lenalidomide, NSD-703813) and Low Dose Dexamethasone (LLD) versus Bortezomib (PS-341, NSC-681239), Lenalidomide and Low Dose Dexamethasone (BLLD) for Induction, in Patients with Previously Untreated Multiple Myeloma without an Intent for Immediate Autologous Stem Cell Transplant Click here to apply for this clinical trial.

CTSU/SWOG S0816
Hodgkin Lymphoma
A Phase II Trial of Response-Adapted Therapy of Stage III-IV Hodgkin Lymphoma Using Early Interim FDG-PET Imaging Click here to apply for this clinical trial.

CTSU/SWOG S0819
Lung Cancer

A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced NSCLC

Click here to apply for this clinical trial.

Duke XELOX-A-D 00010354
Colorectal Cancer
A Phase I Study of Capecitabine, Oxaliplatin, Bevacizumab, and Dasatinib for Patients with Advanced Solid Tumors with Expanded Cohort of Patients with Previously Untreated Metastatic Colorectal Cancer Click here to apply for this clinical trial.

E7373-A001-101
Myelodysplastic Syndrome
A Phase 1 Open-Label, Dose Escalation Study to Determine the Absolute Bioavailability of a Single Oral Dose Administration of Decitabine in Patients with Myelodysplastic Syndrome (MDS) Click here to apply for this clinical trial.

ECOG E-1697
Skin Cancer, Melanoma
Phase III Randomized Study of Four Weeks High Dose IFN-á2b in Stage T2b No, T3a-b No, T4a-b No, and T1-4, N1a, 2a, 3 (microscopic) Melanoma Click here to apply for this clinical trial.

ECOG E1305
Head and Neck
A Phase III Randomized Trial of Chemotherapy With or Without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer Click here to apply for this clinical trial.

ECOG E1505
Lung Cancer, Non Small Cell Lung Cancer
Phase III Randomized trial of adjuvant chemotherapy with or without bevacizumab for patients with completely resected Stage IB (>=4cm)- IIIA Non-Small Cell Lung Cancer Click here to apply for this clinical trial.

ECOG E1508
Lung Cancer

A Randomized Phase II Study of Cisplatin and Etoposide in Combination with Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMCA12 for Patients with Extensive Stage Small Cell Lung Cancer

Click here to apply for this clinical trial.

ECOG E1905
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia

A Randomized Phase II Trial of Azacitidine with or without the Histone Deacetylase Inhibitor Entinostat for the Treatment of Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia (dysplastic type), and Acute Myeloid Leukemia with Multilineage Dysplasia

Click here to apply for this clinical trial.

ECOG E1A06
Multiple Myeloma
An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan, Prednisone and Thalidomide (MPT) Versus Melphalan, Prednisone and Lenalidomide (Revlimid) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy Click here to apply for this clinical trial.

ECOG E2804
Renal Cell Carcinoma
The BEST Trial: A Randomized Phase II Study of VEGF, RAF kinase and mTOR Combination Targeted Therapy (CTT) with Bevacizumab, Sorafenib and Temsirolimus in Advanced Renal Cell Carcinoma Click here to apply for this clinical trial.

ECOG E2805
Renal Cell
ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma Click here to apply for this clinical trial.

ECOG E2903
Chronic Lymphocytic Leukemia

Phase II Trial of Pentostatin, Cyclophosphamide and Rituximab (PCR) followed by Campath-1H for Previously Treat Relapsed or Refractory Patients with Chronic Lymphocytic Leukemia

Click here to apply for this clinical trial.

ECOG E2905
Myelodysplastic Syndrome
Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid) Alone and In Combination with Epoetin Alfa (Procrit) in Subjects with Low or Intermediate-1 Risk MDS and Symptomatic Anemia Click here to apply for this clinical trial.

ECOG E3508
Lung Cancer
A Phase II Randomized Trial of Paclitaxel, Carboplatin, Bevacizumab with or without IMC-A12 in Patients with Advanced Non-Squamous, Non-Small Cell Lung Cancer  Click here to apply for this clinical trial.

ECOG E4203
Colorectal Cancer

Phase II Study of Treatment Selection Based Upon Tumor Thymidylate Synthase Expression in Previously Untreated Patients with Metastatic Colorectal Cancer

Click here to apply for this clinical trial.

ECOG E4508
Lung Cancer

Three-Arm Randomized Phase II Study of Carboplatin and Paclitaxel in Combination with Cetuximab, IMC-A12 or Both for Advanced Non-Small Cell Lung Cancer Patients who Will Not Receive Bevacizumab-Based Therapy

Click here to apply for this clinical trial.

ECOG E4805
Renal Cell Carcinoma
A Randomized Phase II Study to Determine the Effect of 2 Different Doses of AVE0005 (VEGF Trap) in Patients with Metastatic Renal Cell Carcinoma Click here to apply for this clinical trial.

ECOG E5103
Breast Cancer
A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer Click here to apply for this clinical trial.

ECOG E5202
Colorectal Cancer
A Randomized, Phase III Study Comparing 5-FU, Leucovorin and Oxaliplatin vs. 5-FU, Leucovorin, Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers Click here to apply for this clinical trial.

ECOG/CALGB 10403
Acute Lymphoblastic Leukemia
An Intergroup Phase II Clinical Trial for Adolescents and Young Adults with Untreated Acute Lymphoblastic Leukemia (ALL) Click here to apply for this clinical trial.

GOG-0213
Ovarian, Fallopian Tube, Peritoneal Primary Cancer
A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel Alone or in Combination with Bevacizumab (NSC #704865, IND #7921) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Fallopian Tube and Peritoneal Primary Cancer Click here to apply for this clinical trial.

GOG-0240
Cervical Cancer
A Randomized Phase III Trial of Cisplatin Plus Paclitaxel with and without NCI-Supplied Bevacizumab (NSC# 704865, IND# 7921) versus the Non-Platinum Doublet, Topotecan Plus Paclitaxel, with and without NCI-Supplied Bevacizumab, in Stage IVB, Recurrent or Persistent Carcinoma of the Cervix Click here to apply for this clinical trial.

GOG-0250
Uterus
A Randomized Phase III Evaluation of Docetaxel (NSC #628503) and Gemcitabine (NSC #613327) Plus G-CSF with Bevacizumab (NSC #704865, IND #7921) versus Docetaxel (NSC #628503) and Gemcitabine (NSC #613327) Plus G-CSF with Placebo in the Treatment of Recurrent or Advanced Leiomyosarcoma of the Uterus Click here to apply for this clinical trial.

HGT-GCB-058
type 1 Gaucher Disease
A Multicenter Open-Label Treatment Protocol to Observe the Safety of Gene-Activated Human Glucocerebrosidase (GA-GCB, Velaglucerase alfa) Enzyme Replacement Therapy in Newly Diagnosed or Previously Treated (with Imiglucerase) Patients with type 1 Gaucher Disease Click here to apply for this clinical trial.

MCCRC RC0783

Randomized Phase II Trial of Pentostatin, Cyclophosphamide, and Rituximab with or without Concurrent Avastin® for Previously Untreated B-Chronic Lymphocytic Leukemia (CLL)

Click here to apply for this clinical trial.

MTP-OS-403
Osteosarcoma
Liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine (L-MTP-PE): Compassionate Access for High-risk Osteosarcoma Click here to apply for this clinical trial.

NCCTG N07C2
All except Brain and CNS lymphoma
The Use of Wisconsin Ginseng (panax quinquefolius) to Improve Cancer-Related Fatigue: A Randomized, Double-Blind, Placebo-Controlled Phase III Study Click here to apply for this clinical trial.

NCCTG N0821
Lung Cancer
A Phase II First-Line Study of a Combination of Pemetrexed, Carboplatin and Bevacizumab in Advanced Nonsquamous NSCLC Eveluating Efficacy and Tolerability in Elderly Patients (Age >70 Yrs) With Good Performance Status (PS <2) Click here to apply for this clinical trial.

NCCTG N0879
Melanoma

A Randomized Phase II Trial of Carboplatin, Paclitaxel, Bevacizumab, with or without Everolimus for Therapy of Metastatic Malignant Melanoma

Click here to apply for this clinical trial.

NCCTG N08C1

Paclitaxel-Associated Acute Pain Syndrome Natural History Study Click here to apply for this clinical trial.

NCCTG N08C3
Prevention of Chemotherapy Induced Nausea and Vomiting
Phase III Double-Blind, Placebo-Controlled Study of Gabapentin for the Prevention of Delayed CINV (Chemotherapy Induced Nausea and Vomiting) In Patients Receiving Highly Emetogenic Chemotherapy Click here to apply for this clinical trial.

NCCTG N08CA
Ovarian, Tubal, Primary Peritoneal Cancers
The Use of Glutathione (GSH) for Prevention of Paclitaxel/Carboplatin (TAXOL/CBDCA) Induced Peripheral Neuropathy: A Phase III Randomized, Double-Blind Placebo Controlled Study Click here to apply for this clinical trial.

NSABP B-39
Breast Cancer

A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) vs. Partial Breast Irradiation (PBI) for Women with Stage 0, I or II Breast Cancer

Click here to apply for this clinical trial.

NSABP B-41
Breast Cancer
A Randomized Phase III Trial of Neoadjuvant Therapy for Patients with Palpable and Operable HER2-Positive Breast Cancer Comparing the Combination of Trastuzumab Plus Lapatinib to Trastuzumab and to Lapatinib Administered with Weekly Paclitaxel Following AC Accompanied by Correlative Science Studies to Identify Predictors of Pathologic Complete Response Click here to apply for this clinical trial.

NSABP B-43
Breast Cancer
A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy Click here to apply for this clinical trial.

NSABP FRP B-44-I
Breast Cancer
A Multicenter Phase III Randomized Trial of Adjuvant Therapy for Patients with Her2-Positive Node-Positive or High Risk Node-Negative Breast Cancer Comparing Chemotherapy Plus Trastuzumab with Chemotherapy Plus Trastuzumab Plus Bevacizumab Click here to apply for this clinical trial.

NSABP P-5
Colorectal Cancer

Statin Polyp Prevention Trial in Patients with Resected Colon Cancer

Click here to apply for this clinical trial.

PDX-009
Lymphoma
A Phase 1/2a Open-label Study of Pralatrexate and Gemcitabine with Vitamin B12 and Folic Acid Supplementation in Patients with Relapsed or Refractory Lymphoproliferative Malignancies Click here to apply for this clinical trial.

Perifosine 343
Colorectal Cancer
A Phase III Randomized Double-Blind Study to Assess the Efficacy and Safety of Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients with Refractory Advanced Colorectal Cancer Click here to apply for this clinical trial.

TDM4884g
Breast Cancer
An Expanded Access, Open-Label Study of Trastuzumab-MCC-DM1 Administered Intravenously to Patients with HER2-Positive Locally Advanced or Metastatic Breast Cancer Click here to apply for this clinical trial.

USON 05033
Advanced Solid Tumors or Lymphoma
A Phase I Open Label, Multicenter, Dose-Escalation Study to Determine the Maximum Tolerated Dose (MTD), Dose Limiting Toxicity (DLT), Safety and Pharmacokinetics of CGC-11047 when Used in Individual Combinations with 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients with Advanced Solid Tumors or Lymphoma Click here to apply for this clinical trial.

USON 06166
Breast Cancer, Metastatic Breast Cancer
Phase II, multicenter, open-label, clinical trial of Trabectedin (Yondelis®) in Metastatic Breast Cancer Patients with HER2 overexpressing tumors and BRCA1 or BRCA2 mutation carriers Click here to apply for this clinical trial.

USON 06185
Breast Cancer

Randomized Phase II Trial of Letrozole with or without Dasatinib as First-Line Treatment for Hormone Receptor-Positive, HER2-Negative Post-Menopausal Breast Cancer that is Unresectable, Locally Recurrent or Metastatic

Click here to apply for this clinical trial.

USON 07119
Breast Cancer
A Multicenter Phase III Randomized Trial of Adjuvant Therapy for Patients with HER2-Positive Node-Positive or High Risk Node-Negative Breast Cancer Comparing Chemotherapy Plus Trastuzumab with Chemotherapy Plus Trastuzumab Plus Bevacizumab Click here to apply for this clinical trial.

USON 07132
Breast Cancer
A Phase III Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women with Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer Click here to apply for this clinical trial.

USON 07141
Colorectal Cancer
A Multi-center, Open-label, Randomized, Phase 2 Clinical Trial Evaluating Safety and Efficacy of FOLFIRI with Either Panitumumab or Bevacizumab as Second-line Treatment in Subjects with Metastatic Colorectal Cancer Click here to apply for this clinical trial.

USON 07142
Breast Cancer
A Phase 2, Open-Label Study of EZN-2208 (PEG-SN38) in Patients with Previously Treated Metastatic Breast Cancer Click here to apply for this clinical trial.

USON 07152
Non-Hodgkin Lymphoma (NHL), Mantle Cell Lymphoma

An Open-Label, Randomized, Parallel-Group Study of Bendamustine Hydrochloride and Rituximab (BR) Compared With Rituximab, Cyclophosphamide, Vincristine, and Prednisone (R-CVP) or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in the First-Line Treatment of Patients with Advanced Indolent Non-Hodgkin’s Lymphoma (NHL) or Mantle Cell Lymphoma (MCL)

Click here to apply for this clinical trial.

USON 07178/RTOG 0617
Lung Cancer
A Randomized Phase III Comparison of Standard-Dose (60 Gy) versus High-Dose (74 Gy) Conformal Radiotherapy with Concurrent and Consolidation Carboplatin/Paclitaxel +/- Cetuximab (IND# 103444) in Patients with Stage IIIA/IIIB Non-Small Cell Lung Cancer Click here to apply for this clinical trial.

USON 08007
Breast Cancer
Phase II Trial of Ixabepilone plus Carboplatin in Patients with Metastatic Breast Cancer Click here to apply for this clinical trial.

USON 08008
Advanced Solid Tumors
A Phase 1b, Multicenter, Dose-Escalation Study of LY573636-sodium in Combination with 1) Gemcitabine HCl or 2) Docetaxel or 3) Temozolomide or 4) Cisplatin in Patients with Advanced Solid Tumors Click here to apply for this clinical trial.

USON 08031
Solid Tumors

A Multicenter, Phase 1, Open-Label, Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of NKTR-102 (NKT-10002; PEG-Irinotecan) in Patients with Refractory Solid Tumors

Click here to apply for this clinical trial.

USON 08035
Lung Cancer
A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long-term Safety and Efficacy of Darbepoetin Alfa Administered at 500 µg Once-Every-3-Weeks in Anemic Subjects With Advanced Stage Non-small Cell Lung Cancer Receiving Multi-cycle Chemotherapy Click here to apply for this clinical trial.

USON 08044
Lung Cancer

Randomized, Open-Label, Phase 3 Study of Pemetrexed plus Carboplatin and Bevacizumab Followed by Maintenance Pemetrexed and Bevacizumab versus Paclitaxel plus Carboplatin and Bevacizumab Followed by Maintenance Bevacizumab in Patients with Stage IIIB or IV Nonsquamous Non-Small Cell Lung Cancer

Click here to apply for this clinical trial.

USON 08055
Gastrointestinal Stromal Tumors (GIST)
A randomized, multi-center phase III study to evaluate the efficacy and safety of nilotinib versus imatinib in adult patients with unresectable or metastatic gastrointestinal stromal tumors (GIST) Click here to apply for this clinical trial.

USON 08079/RTOG 0534
Prostate Cancer
A Phase III Trial Of Short Term Androgen Deprivation With Pelvic Lymph Node Or Prostate Bed Only Radiotherapy In Prostate Cancer Patients With A Rising PSA After Radical Prostatectomy Click here to apply for this clinical trial.

USON 08087
Mantle Cell Lymphoma
An open-label, single-arm phase II study of RAD001 in patients with mantle cell lymphoma who are refractory or intolerant to Velcade Click here to apply for this clinical trial.

USON 08094
Lung Cancer
A Phase III, Randomized, Double-Blind, Placebo-Controlled Multi-Center Study of ASA404 in Combination with Docetaxel in Second-Line Treatment of Patients with Locally Advanced or Metastatic (Stage IIIb/IV) Non-Small Cell Lung Cancer (NSCLC) Click here to apply for this clinical trial.

USON 08101
Solid Tumors
A Phase 1, Multicenter, Open-Label, Single-Arm, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Antitumor Activity of MEDI-575, a Fully Human Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor-alpha (PDGFR-alpha), in Subjects with Advanced Solid Tumors Refractory to Standard Therapy or for Which No Standard Therapy Exists Click here to apply for this clinical trial.

USON 08113
Colorectal Cancer

A Randomized, Multicenter, Phase 2 Study to Compare the Efficacy of Panitumumab in Combination With mFOLFOX6 to the Efficacy of Bevacizumab in Combination With mFOLFOX6 in Patients With Previously Untreated, KRAS Wild-Type, Unresectable, Metastatic Colorectal Cancer

Click here to apply for this clinical trial.

USON 08130
Thymic Carcinoma

Phase II Study of Oral PHA-848125AC in Patients with Thymic Carcinoma Previously Treated with Chemotherapy

Click here to apply for this clinical trial.

USON 08137
Colorectal Cancer
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of FOLFIRI in Combination With AMG 479 or AMG 655 Versus FOLFIRI for the Second-Line Treatment of KRAS-Mutant Colorectal Carcinoma Click here to apply for this clinical trial.

USON 08183/RTOG 0436
Esophageal Cancer
A Phase III Trial Evaluating The Addition Of Cetuximab To Paclitaxel, Cisplatin, And Radiation For Patients With Esophageal Cancer Who Are Treated Without Surgery Click here to apply for this clinical trial.

USON 08209
Multiple Myeloma

A Phase III Randomized Study to Assess the Efficacy and Safety of Perifosine Added to the Combination of Bortezomib and Dexamethasone in Multiple Myeloma Patients Previously Treated with Bortezomib

Click here to apply for this clinical trial.

USON 08210
Metastatic Cancer
A Phase 1 Dose-Escalation Study of LY2382770, a TGF-beta Monoclonal Antibody, in Patients with Metastatic Cancer Click here to apply for this clinical trial.

USON 08217
Breast Cancer
A randomized phase III, double-blind, placebo-controlled multicenter trial of everolimus in combination with trastuzumab and paclitaxel, as first line therapy in women with HER2-positive locally advanced or metastatic breast cancer Click here to apply for this clinical trial.

USON 08223
Breast Cancer

A Randomized Phase III, Double-Blind, Placebo-Controlled Multicenter Trial of Daily Everolimus in Combination with Trastuzumab and Vinorelbine, in Pretreated Women with HER2/neu Over-expressing Locally Advanced or Metastatic Breast Cancer

Click here to apply for this clinical trial.

USON 09015
Lung Cancer

A Phase 2, Multicenter, Randomized Study of Two Different Dose Regimens of Eribulin Mesylate in Combination with Intermittent Erlotinib in Patients with Previously Treated, Advanced Non-Small Cell Lung Cancer

Click here to apply for this clinical trial.

USON 09046
Lung Cancer
A Phase 1/2 Study of Aflibercept Administered in Combination with Pemetrexed and Cisplatin in Patients with Advanced Carcinoma Click here to apply for this clinical trial.

USON 09054
Breast Cancer
A randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase 3 Study of Denosumab as Adjuvant Treatment for Women with Early-Stage Breast Cancer at High Risk of Recurrence (D-CARE) Click here to apply for this clinical trial.

USON 09057/RTOG 0825
Glioblastoma

Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide Plus Bevacizumab Versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma

Click here to apply for this clinical trial.

USON 09064
Non-Hodgkin Lymphoma (NHL)
An Open-Label, Randomized, Phase 2 Study to Assess the Effectiveness of RCHOP With or Without VELCADE in Previously Untreated Patients with Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma Click here to apply for this clinical trial.

USON 09073
Prostate Cancer

A Phase 3 Study to Evaluate the Efficacy and Safety of Docetaxel and Prednisone with or without Lenalidomide in Subjects with Castrate-Resistant Prostate Cancer

Click here to apply for this clinical trial.

USON 09078
Lung Cancer
A Phase 2 Study to Evaluate LY2603618 in Combination with Pemetrexed in Patients with Advanced or Metastatic Non-small Cell Lung Cancer Click here to apply for this clinical trial.

USON 09101
Prostate Cancer, Liver, Melanoma, Ovarian, Primary Peritoneal, and Fallopian Tube Carcinoma
A Randomized Discontinuation Study of XL184 in Subjects with Advanced Solid Tumors Click here to apply for this clinical trial.

USON 09107
Breast Cancer

An Open-Label Randomized, Parallel, Two-Arm Phase II Study Comparing BMS-690514 + Letrozole With Lapatinib + Letrozole in Recurrent and Metastatic Breast Cancer Patients Who Are Hormone Receptor Positive Despite HER2 status and Who Relapsed While Receiving or After Completing Adjuvant Antiendocrine Therapy

Click here to apply for this clinical trial.

USON 09119
Melanoma
A Randomized Phase III Study of Tasisulam Administered as an Intravenous Infusion on Day 1 of a 28-Day Cycle vs. Paclitaxel as Second-Line Treatment in Patients with Metastatic Melanoma Click here to apply for this clinical trial.

USON 09129
Symptomatic Deep-Vein Thrombosis and/or Pulmonary Embolism
A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel-Group, Multicenter, Multi-National Study for the Evaluation of Efficacy and Safety of (LMW) Heparin/Edoxaban Versus (LMW) Heparin/Warfarin in Subjects with Symptomatic Deep-Vein Thrombosis and/or Pulmonary Embolism Click here to apply for this clinical trial.

USON 09132/RTOG/NSABP B-43
Breast Cancer
A Phase III Clinical Trial Comparing Trastuzumab Given Concurently with Radiation and Radiation Alone for Women with Her2-Postive Ductal Carcinoma In Situ (DCIS) Resected by Lumpectomy Click here to apply for this clinical trial.

USON 09133
Breast Cancer
Triple Negative Breast Cancer Biomarker Study Click here to apply for this clinical trial.

USON 09141
Multiple Myeloma

The Multiple Myeloma Disease Registry - Registry Protocol (CONNECTTM MM)

Click here to apply for this clinical trial.

USON 09152
Myelodysplastic Syndromes

A multi-center, randomized, double-blind, placebo-controlled clinical trial of deferasirox in patients with myelodysplastic syndromes (low/int-1 risk) and transfusional iron overload (TELESTO)

Click here to apply for this clinical trial.

USON 09182
Hepatocellular

A randomized phase III, double-blind, placebo-controlled, multi-center study to evaluate the efficacy and safety of everolimus (RAD001) in adult patients with advanced Hepatocellular Carcinoma after failure of sorafenib treatment

Click here to apply for this clinical trial.

USON 09183
Lung Cancer
An Open-Label, Multicenter, Randomized Phase Ib/II Study of Eribulin Mesylate Administered in Combination with Pemetrexed vs Pemetrexed Alone as Second Line Therapy in Patients with Stage IIIB or IV Nonsquamous Non-Small Cell Lung Cancer Click here to apply for this clinical trial.

USON 09185
Breast Cancer
An Open-Label, Expanded Access Protocol of Iniparib in Combination with Gemcitabine/Carboplatin in Patients with ER-, PR-, and HER2-Negative Metastatic Breast Cancer Click here to apply for this clinical trial.

USON 09186
Colorectal Cancer

An Open-Label, Multicenter, Randomized Phase Ib/II Study of FOLFIRI Alone Versus FOLFIRI Plus Bevacizumab Versus FOLFIRI Plus E7820 as Second-Line Therapy in Patients with Locally Advanced or Metastatic Colorectal Cancer

Click here to apply for this clinical trial.

USON 09187
Bladder Cancer
An Open-Label, Multicenter, Randomized Phase Ib/II Study of Eribulin Mesylate Administered in Combination with Gemcitabine Plus Cisplatin Versus Gemcitabine Plus Cisplatin Alone as First-Line Therapy for Locally Advanced or Metastatic Bladder Cancer Click here to apply for this clinical trial.

USON 09200/RTOG 0815
Prostate Cancer

A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer

Click here to apply for this clinical trial.

USON 10011/GOG-0249
Endometrial Cancer

A Phase III Trial of Pelvic Radiation Therapy versus Vaginal Cuff Brachytherapy Followed by Paclitaxel/Carboplatin in Patients with High-Risk, Early Stage Endometrial Cancer

Click here to apply for this clinical trial.

USON 10034
Chronic Lymphocytic Leukemia
The Chronic Lymphocytic Leukemia Disease Registry, CONNECTTM CLL Click here to apply for this clinical trial.

USON 10052
Melanoma
An Open-Label, 2-Cohort, Multicenter, Phase 2 Study of E7080 in Previously Treated Subjects With Unresectable Stage III or Stage IV Melanoma Click here to apply for this clinical trial.

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