Kelly Casteel, MD

Medical Oncologist / Hematologist

Kelly Casteel, MD  | Oncologist at Rocky Mountain Cancer Centers


1760 E. Ken Pratt Blvd. Ste. 302
Longmont, CO 80504


Request an Appointment

Secondary Location(s)

Longmont Breast Specialists

1760 E. Ken Pratt Blvd. Ste. 301
Longmont, CO 80504


Request an Appointment

About Kelly Casteel, MD

Dr. Kelly Casteel is board certified in hematology and medical oncology. She completed her fellowship training at MD Anderson Cancer Center, after which she served as faculty. While at MD Anderson, she was recognized as a leader in training future oncologists and was acknowledged as a top performer in patient care, achieving patient satisfaction scores in the top 1% nationally.

Dr. Casteel treats all types of cancer and blood disorders. She has a special interest in blood diseases including anemia, iron deficiency, blood clotting disorders, anticoagulation management, platelet disorders, myeloproliferative neoplasms, hemochromatosis, leukemia, lymphoma, and myeloma. She maintains close professional relationships with local and national experts in blood diseases and cancer, which, together with access to clinical trials through The US Oncology Network and the multi-disciplinary team approach at RMCC, allows her to provide expert care to all patients.

Board Certifications

Internal Medicine
Medical Oncology


  • Anemia
  • Blood Cancers
  • Bleeding Disorders
    • Hemophilia
    • Von Willebrand disease
  • Breast Cancers
  • Clotting Disorders
    • Deep vein thrombosis
    • Pulmonary embolism
    • Hypercoagulable diseases
  • Gastrointestinal Cancers
    • Anal Cancer
    • Biliary Cancer
    • Colon Cancer
    • Liver Cancer
    • Rectal Cancer
    • Stomach Cancer
  • Genitourinary Cancers
  • Gynecologic Cancers
    • Cervical Cancer
    • Ovarian Cancer
    • Uterine Cancer
  • Iron Disorders
    • Hemochromatosis
    • Iron Deficiency
  • Lung Cancer
  • Platelet Disorders
    • Essential Thrombocytosis
    • Immune Thrombocytopenic Purpura
    • Platelet Disorders of Pregnancy
    • Rare Platelet Disorders
  • Skin Cancer



Hematology & Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX


Internal Medicine and Pediatrics, University of Texas at Houston McGovern Medical School, Houston, TX

Medical School

Case Western Reserve University School of Medicine, Cleveland, OH

Patient Care Philosophy

Communication is key in medicine. From the moment I first meet a patient, I strive to communicate clearly and as often as needed to ensure that the patient, their family members, and the other members of their medical team understand the diagnosis, prognosis, and treatment plan. I encourage my patients and their families to write down any questions or worries they have so that we can address them at each visit. By prioritizing each patient’s concerns, I learn about their individual needs and establish the trust needed to formulate the best plan for their specific diagnosis.

Cancer treatment is complex and requires a multidisciplinary team approach to achieve the best patient outcomes. Through research efforts and access to a national network of experts at the cutting edge of cancer treatment, our team at RMCC brings world class care to our community. I am proud to provide both expertise and compassionate care to my patients and their families.


Additional Information

American Society of Clinical Oncology
American Society of Hematology

Peer-reviewed Journal Articles

Westerman ME, Bree KK, Msaouel P, Kukreja JB, Mantaring C, Rukundo I, Garcia Gonzalez M, Gregg JR, Casteel KN, Matin SF. (2022). Apixaban vs Enoxaparin for Post-Surgical Extended-Duration Venous Thromboembolic Event Prophylaxis: A Prospective Quality Improvement Study. Journal of Urology. 2022 Oct;208(4):886-895. 

Jara MA, Casteel KN, Afshar-Kharghan V, Subbiah V, Wing S, and Hu MI. (2021). Paraneoplastic eosinophilia (PNE): A Rare Finding in a Patient with Metastatic Medullary Thyroid Carcinoma. Journal of the Endocrine Society. 5(1), 2021: A896.

Yang W, Tholpady A, Casteel K, Rojas-Hernandez C. (2020). Platelet-refractoriness and the clinical impact in leukemia population at a metropolitan academic cancer center. Leuk Lymphoma. 2020 Apr;61(4):996-998. doi: 10.1080/10428194.2019.1697810. PMID: 31795873.

Jain P, Casteel K, Allen CE, McClain KL, Wang S, Konoplev S, Jabbour EJ, Nogueras Gonzalez G, Huang X, Miller S, Abdelall W, Tamamyan G, Kadia TM, Borthakur G, Estrov Z, Ravandi F, Garcia-Manero G, Cortes JE, Kantarjian HM, Daver N. (2016). Elevated Ferritin Predicts for Inferior Survival in Patients with Acute Myeloid Leukemia and May be an Early marker of a Underlying Systemic Pathologic Inflammation. Blood. 2016 Dec; 128(22): 2791.

Swails J, Gulbis B, Casteel K, and Orlander P. (2016). Team-Based Evaluation of Inter- Professional Collaboration Skills Identifies More Deficiencies Compared with Individual Evaluations. Academic Internal Medicine Insight, 13:4. 

Other Articles

Casteel K. (2021). Editorial Commentary on Full Dose Blood Thinners Decreased Need for Life Support and Improved Outcomes in Hospitalized COVID-19 Patients in International Trial. PracticeUpdate website. Available at: thinners-decreased-need-for-life-support-and-improved-outcomes-in-hospitalized-covid-19- patients-in-international-trial/113208/12/18/2

Casteel K. (2020). Editorial Commentary on Dabigatran Etexilate for the Treatment of Acute Venous Thromboembolism in Children. PracticeUpdate website. Available at: thromboembolism-in-children/110620/12/18/1

Casteel K. (2020). 2020 Top Stories in Benign Hematology: Antithrombotic Therapy and COVID- 19. PracticeUpdate website. Available at: stories-in-benign-hematology-antithrombotic-therapy-and-covid-19/110454/12/18/3

Casteel K, Kroll M, and Naik R. (2020). COVID 19: Through a Hematologic Filter. PracticeUpdate website. Available at: severe-novel-coronavirus-pneumonia/99140/12/18/1

Casteel K. (2020). Editorial Commentary on Low VWF Levels in Children and Lack of Association with Bleeding in Children Undergoing Tonsillectomy. PracticeUpdate website. Available at: association-with-bleeding-in-children-undergoing-tonsillectomy/95323/12/18/1

Casteel K. (2020). Editorial Commentary on Blood Loss from Laboratory Testing, Anemia, and Red Blood Cell Transfusion in the ICU. PracticeUpdate website. Available at: blood-cell-transfusion-in-the-icu/94542/12/18/1

Casteel K. (2019). Editorial Commentary on Screening for Iron Deficiency in Early Childhood Using Serum Ferritin in the Primary Care Setting. PracticeUpdate website. Available at: Https:// serum-ferritin-in-the-primary-care-setting/77315/65/18/1.

Casteel K and Kroll M. (2018). A Surgeon’s Guide to DOACs. PracticeUpdate website. Available at: Https:// 

Book Chapters

Casteel K, Kroll M. (2022). Cancer Associated Thrombosis. In: Kantarjian H., Wolff R. and Rieber A., (eds) The MD Anderson Manual of Medical Oncology (4th ed). McGraw Hill.

Casteel K, Kroll M. (2021). Hypercoagulable States. In: Levine G., (ed) Cardiology Secrets (6th ed). New York: Elsevier.

Casteel K, Kroll M. (2019). Benign Hematological Diseases in Cancer Patients. In: Nates J., Price K. (eds) Oncologic Critical Care. Springer, Cham.

Casteel K. (2015). Klinefelter Syndrome. In E. Toy, R. Yetman, M. Hormann, M. McNeese, S. Lahoti, M. J. Sanders, and A. Geltemeyer, Case Files Pediatrics (5th ed.). New York: McGraw- Hill Education/Medical.

Casteel K. (2015). Megaloblastic Anemia. In E. Toy, R. Yetman, M. Hormann, M. McNeese, S. Lahoti, M. J. Sanders, and A. Geltemeyer, Case Files Pediatrics (5th ed.). New York: McGraw- Hill Education/Medical.