Colorectal Cancer

A sample of the colon tumor is sent to a lab where the cells are evaluated for any "biomarkers" that indicate a genetic mutation or protein overgrowth is causing cancer to grow. The results of biomarker tests make it possible for your oncologist to create a highly personalized treatment plan that includes targeted therapy or immunotherapy drugs designed to counteract the specific biomarker. If no biomarkers were found in the tumor sample, other treatments are planned for the patient.

The majority of colorectal cancers are not caused by an inherited genetic change. About 5-10% of cases are linked to hereditary conditions:

• Lynch syndrome (also called hereditary nonpolyposis colorectal cancer or HNPCC)
• Familial adenomatous polyposis (FAP)

If you have a strong family history of colorectal cancer or related cancers (such as endometrial, ovarian, or stomach cancer), your doctor may recommend genetic counseling or testing. Early screening and regular checkups are important for people with a family history to help detect cancer when it is easier to treat successfully.

Colorectal cancer can spread, or metastasize, to other parts of the body if it moves beyond the colon or rectum. The most common places it spreads to are the liver and the lungs. It can also spread to the lining of the abdominal cavity (peritoneum), the bones, and, less commonly, the brain. The location of the cancer outside the colon affects the symptoms experienced and also influences the treatment plan. If the tumor is large or colorectal cancer has developed outside of the colon at the time of diagnosis, surgery may not be possible, but other treatments can be given to shrink the cancer.

The specific side effects of colorectal cancer treatment depend on the therapies included in the personalized treatment plan and your response to them. Common side effects include fatigue, nausea and vomiting, neuropathy in the hands and feet, and changes in appetite or taste. Patients receiving FOLFOX chemotherapy may become especially sensitive to heat and cold on their hands and feet.

FOLFOX is a common combination of three chemotherapy drugs often used to treat colorectal cancer. Hair loss is not common with FOLFOX chemotherapy. Some people may notice thinning hair, but most do not lose all their hair. If hair thinning does occur, it’s often temporary, and hair usually grows back after treatment ends. Talk to your oncology nurse, advanced practice provider, or oncologist about any treatment side effects you may be experiencing. They can often offer help to keep them minimized.

Clinical trials offer access to new treatments for colon and rectal cancer that aren't widely available yet. Current studies are especially focused on developing targeted therapies for genetic changes. RMCC participates in several colorectal cancer clinical trials, providing patients with opportunities to explore innovative treatments. Not every patient qualifies, but we are happy to review options for you and make a recommendation for participation if you qualify for one or more trials. Talk with your oncologist about whether a trial may be right for you.

For over 30 years, RMCC has been a leader in delivering world-class cancer care to patients across Colorado. Our oncologists and advanced practice providers were trained in the most renowned cancer centers in the United States and beyond, bringing their expertise to you. They are dedicated to being innovative and forward-thinking, never settling and always seeking the right treatment for their colorectal cancer patients. Meet our colorectal cancer specialists.

Our financial counselors will review your insurance plan's cancer benefits and then meet with you to discuss what will be covered and any out-of-pocket expenses. It's important to note that receiving cancer care at an independent cancer center like Rocky Mountain Cancer Centers results in a lower cost for patients when compared to cancer care at hospital outpatient departments. According to the Community Oncology Alliance, cancer treatment can cost up to 50% less in an independent oncology practice compared to a hospital-affiliated outpatient department.

Receiving affordable cancer care does not mean compromising on quality. We provide the same quality of care as hospital-affiliated oncology departments using advanced technologies and personalized treatments at a more affordable price.