John M. Burke, MD

Abstracts

Tilly H et al. Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma. N Engl J Med 2021, abstract.

Burke JM et al. Real-world characteristics of patients with peripheral T-cell lymphoma receiving frontline brentuximab vedotin with chemotherapy: a retrospective analysis with propensity score matching. American Society of Hematology 2020, abstract 3418.

Belada D et al. A phase 1b, open-label, randomized study to assess safety and preliminary efficacy of tafasitamab (MOR208) or tafasitamab + lenalidomide in addition to R-CHOP in patients with newly diagnosed diffuse large B-cell lymphoma: analysis of the safety run-in phase. American Society of Hematology 2020, abstract 3028.

Flinn IW et al. Debulking regimens prior to initiating venetoclax therapy in untreated patients with chronic lymphocytic leukemia: interim results from a phase 3b study. American Society of Hematology 2020, abstract 3151.

Gribben JG et al. Umbralisib plus ublituximab (U2) is superior to Obinutuzumab plus chlorambucil (O+Chl) in patients with treatment naïve (TN) and relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL): results from the phase 3 Unity-CLL study. American Society of Hematology 2020, abstract 543.

Philllips TJ et al. Real-world characteristics of patients with classical Hodgkin lymphoma receiving frontline brentuximab vedotin with chemotherapy: a retrospective analysis with propensity score matching. American Society of Hematology 2020, abstract 2499.

Shadman M et al. Phase 2 study of zanubrutinib in patients with relapsed/refractory B-cell malignancies intolerant to ibrutinib/acalabrutinib. American Society of Hematology 2020, abstract 2947.

Shah NN et al. Preliminary results of an ongoing phase 1 dose escalation study of the novel anti-CD74 antibody drug conjugate (ADC), STRO-001, in patients with B-cell non-Hodgkin lymphoma. American Society of Hematology 2020, abstract 3030.

Zinzani PL et al. Umbralisib, the once daily dual inhibitor of PI3Kd and casein kinase-1e demonstrates clinical activity in patients with relapsed or refractory indolent non-Hodgkin lymphoma: results from the phase 2 global Unity-NHL trial. American Society of Hematology 2020, abstract 2934.

Manuscripts

Choueiri T, Tomczak P, Park S...Burke JM, et al. Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma. N Engl J Med 2021; 385:683-694.

Burke JM, Morschhauser F, Andorsky D, Lee C, Sharman JP. Antibody-drug conjugates for previously treated aggressive lymphomas: focus on polatuzumab vedotin. Expert Review of Clinical Pharmacology 2020; 13(10): 1073-83.

Burke JM, Shustov A, Essell J, Patel-Donnelly D, Yang J, Chen R, Ye W, Shi W, Assouline S, Sharman J. An open-label, phase II trial of entospletinib (GS-9973), a selective spleen tyrosine kinase inhibitor, in diffuse large B-cell lymphoma. Clin Lymphoma Myeloma Leuk 2018; 18(8):e327-e331.

Burke JM, van der Jagt RHC, Kahl BS, Wood P, Hawkins, TE, MacDonald D, Hertzberg M, Simpson D, Craig M, Kolibaba K, Issa S, Munteanu M, Victor TW, Flinn IW. Differences in quality of life between bendamustine-rituximab and R-CHOP/R-CVP in patients with previously untreated advanced indolent non-Hodgkin lymphoma or mantle cell lymphoma. Clinical Lymphoma, Myeloma, & Leukemia 2016; (16(4):182-190.

Burke JM, Van der Jagt RHC, Flinn IW, Craig MD, Chen L, Morganroth J, Munteanu MC, MacDonald DA. Effect of bendamustine in combination with rituximab on QT interval duration in patients with advanced de novo indolent non-Hodgkin or mantle cell lymphoma. Cancer Chemotherapy and Pharmacology 2015; 76(1):211-216.

Darwish M, Burke JM, Hellriegel E, Robertson P, Phillips L, Ludwig E, Munteanu MC, Bond M. An evaluation of the potential for drug-drug interactions between bendamustine and rituximab in indolent non-Hodgkin lymphoma and mantle cell lymphoma. Cancer Chemother Pharmacol 2014; 73(6):1119-27.

Flinn IW, van der Jagt R, Kahl B, Wood P, Hawkins T, MacDonald D, Simpson D, Kolibaba K, Issa S, Chang J, Trotman J, Hallman D, Chen L, Burke JM. First-line treatment of patients with indolent non-Hodgkin lymphoma or mantle-cell lymphoma with bendamustine plus rituximab versus R-CHOP or R-CVP: results of the BRIGHT 5-year follow-up study. J Clin Oncol 2019; 37(12):984-91.

Flinn IW, van der Jagt R, Kahl BS, Wood P, Hawkins TE, MacDonald D, Hertzberg M, Kwan Y, Simpson D, Craig M, Kolibaba K, Issa S, Clementi R, Hallman DM, Munteanu M, Chen L, Burke JM. Open-label, randomized, noninferiority study of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of advanced indolent NHL or MCL: the BRIGHT study. Blood 2014; 123(19):2944-52.

Fowler NH, Samaniego F, Jurczak W…Burke JM, et al. Umbralisib, a dual PI3K /CK1 inhibitor, in patients with relapsed or refractory indolent lymphoma [published online ahead of print March 8, 2021]. J Clin Oncol 2021.

Grunwald MR, Kuter DJ, Altomare I, Burke JM, et al. Treatment patterns and blood counts in patients with polycythemia vera treated with hydroxyurea in the United States: an analysis from the REVEAL study. Clin Lymphoma Myeloma Leukemia 2020; in press.

Grunwald MR, Burke JM, Kuter DJ, Gerds AT, Stein B, Walshauser MA, Parasuraman S, Colucci P, Paranagama D, Savona MR, Mesa R. Symptom burden and blood counts in patients with polycythemia vera in the United States: an analysis from the REVEAL study. Clin Lymphoma Myeloma Leuk 2019; 19(9):579-84.e1.

Hlubocky FJ, Symington BE, McFarland, …Burke JM…et al. Impact of the COVID-19 pandemic on oncologist burnout, emotional well-being, and moral distress: considerations for the cancer organization’s response for readiness, mitigation, and resilience. JCO Oncology Practice 2021, online.

Munteanu MC, Burke JM. Barriers to lymphoma clinical practice guideline adherence: a pilot mixed-methods research study. J Clin Pathways 2019; 5(3):31-38,S1-3.

Sharman JP, Brander DM, Mato AR…Burke JM, et al. Ublituximab plus ibrutinib versus ibrutinib alone for patients with relapsed or refractory high-risk chronic lymphocytic leukaemia (GENUINE): a phase 3, multicentre, open-label, randomized trial. Lancet Haematology, online February 2021.

Sharman JP, Burke JM, Yimer HA, Boxer MA, Babu S, Li J, Mun Y, Danilov AV. Phase 2 multicenter GIBB study of obinutuzumab plus bendamustine in previously untreated patients with chronic lymphocytic leukemia. Leukemia & Lymphoma, published online 26 Nov 2020.

Sharman JP, Farber CM, Mahadevan D, Schreeder MT, Brooks HD, Kolibaba KS, Fanning S, Klein L, Greenwald DR, Sportelli P, Miskin HP, Weiss MS, and Burke JM. Ublituximab (TG-1101), a novel glycoengineered anti-CD20 antibody, in combination with ibrutinib is safe and highly active in patients with relapsed and/or refractory chronic lymphocytic leukemia: results of a phase 2 trial. British Journal of Hematology 2017, 176(3):412-20.

Sharman JP, Wheler JJ, Einhorn L, Dowlati A, Shapiro GI, Hilton J, Burke JM, Siddiqi T, Whiting N, Jalal SI. A phase 2, open-label study of brentuximab vedotin in patients with CD30-expressing solid tumors. Investigational New Drugs 2019; 37(4):738-47.

Vitolo U, Trneny M, Belada D, Burke JM, et al. Obinutuzumab or rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in previously untreated diffuse large B-cell lymphoma. Journal of Clinical Oncology 2017; 2017; 35(31):3529-37.

Wilfong L, Ginsburg A, Hoverman JR, Burke JM, Busby LT, Hsieh A, Konduri K, Neubauer MA. Treatment pathways for first-line metastatic non-small cell lung cancer: cost and survival. J Clin Pathways 2020; 6(8):52-7.

Yimer H, Melear J, Faber E, Bensinger WI, Burke JM, Narang M, Stevens D, Gunawardena S, Lutska Y, Qi K, Ukropec J, Qi M, Lin TS, and Rifkin RM. Daratumumab, bortezomib, cyclophosphamide and dexamethasone in newly diagnosed and relapsed multiple myeloma: LYRA study. Brit J Haematol 2019; 185(3).